The University of Debrecen has participated in the development of vaccines against the most common pathogens causing diarrhea. The institution performed clinical trials on healthy volunteers on behalf of a biotechnology company founded by Hungarian experts.
Bacterial diarrhea is a significant problem for foreigners arriving in developing countries. Vaccines developed at the university against the two most common pathogens specifically causing diarrhea – Shigella and Enterotoxic Escherichia coli – were tested in a phase I study.
The aim of the study was to determine the optimal dose in addition to efficacy and safety.
A similar study has not been performed at the University of Debrecen before. During the procedure, the University of Debrecen represented significant added value in research and development
– Dénes Páll told.
They added that the effectiveness of the vaccine, with favorable results, could be tested in the next step already in patients in developing countries.