Vaccine development against the most common pathogens that cause diarrhea at the University of Debrecen

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The University of Debrecen has participated in the development of vaccines against the most common pathogens causing diarrhea. The institution performed clinical trials on healthy volunteers on behalf of a biotechnology company founded by Hungarian experts.

Bacterial diarrhea is a significant problem for foreigners arriving in developing countries. Vaccines developed at the university against the two most common pathogens specifically causing diarrhea – Shigella and Enterotoxic Escherichia coli – were tested in a phase I study.

The aim of the study was to determine the optimal dose in addition to efficacy and safety.

A similar study has not been performed at the University of Debrecen before. During the procedure, the University of Debrecen represented significant added value in research and development

– Dénes Páll told.

They added that the effectiveness of the vaccine, with favorable results, could be tested in the next step already in patients in developing countries.

 

hirek.unideb.hu

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